2025 College Football Week 9 Betting Preview
In College Football Week 8, another heavyweight fell as No. 2 Miami lost straight up to unranked Louisville at home on Friday night. This week, undefeated Texas A&M heads to Baton Rouge to take on LSU, and undefeated Indiana hosts pesky UCLA. Which teams should be on your radar to cover spreads and win outright as dogs? Check out a list of six great picks for College Football Week 9, along with college football odds and analysis.
Top 2025 College Football Week 9 Games to Bet On
Every spot in the Top 25 ranking has changed from last week, except Ohio State at No. 1. See where other top teams land.https://t.co/7dTTUiSC1j
— AP Top 25 (@AP_Top25) October 19, 2025
Virginia vs. North Carolina
- When: Saturday, October 25th. 12:00 p.m. ET
- strong>College Football Week 9 Odds: Virginia -385 / North Carolina +300
Maybe choosing Bill Belichick as your head coach wasn’t the right move. Bill has moved on from football, as evidenced by his love for his new girlfriend. There’s nothing wrong with that. Who wouldn’t want an easy on the eyes girlfriend about fifty years younger than you when you’re in your seventies?
But if you aren’t obsessed with the pigskin, you can’t hang in Division 1 college football. That’s a fact. So the Heels have two wins against Richmond and Charlotte and face an ACC rival that believes it can win the division. The Cavaliers cover.
2025 College Football Week 9 Pick: Virginia
Ole Miss vs. Oklahoma
- When: Saturday, October 25th. 12:00 p.m. ET
- strong>College Football Week 9 Odds: Ole Miss +150 / Oklahoma -182
Ole Miss comes off a tough road loss to Georgia in Athens. It’s not easy to face the Dawgs and then go on the road to Norman, a place almost as equally challenging to win as Georgia.
Still, the Rebels were in the game until the end. It took a massive effort from Georgia’s offense to get the victory. Oklahoma’s offense doesn’t seem as tight as Georgia’s. John Mateer had a decent game versus South Carolina after playing awful football against Texas. The hook should matter in this game, though. Back the Rebels.
2025 College Football Week 9 Pick: Ole Miss
Texas A&M vs. LSU
- When: Saturday, October 25th. 7:30 p.m. ET0
- strong>College Football Week 9 Odds: Texas A&M -137 / LSU +115
This is a decent moneyline play on LSU. The Tigers offer +120 early. So jump on those odds if you can. A&M is a quality team, which is why they are undefeated.
But the Aggies almost lost to Arkansas on the road in a 45-42 game. Giving up 42 to the Hogs isn’t a good sign heading to Baton Rouge to face a desperate Brian Kelly team. Also, the LSU defense is elite, the best A&M has faced all season. LSU gets it done in the ML.
2025 College Football Week 9 Pick: LSU
Wisconsin vs. Oregon
- When: Saturday, October 25th. 7:00 p.m. ET
- strong>College Football Week 9 Odds: Texas Tech -455 / Arizona State +310
Luke Fickell is a better football coach than he’s shown this season. Who knows why, but Fickell can’t get the most out of his players, which is why the Badgers are in the midst of one of their worst seasons in history.
Wisconsin can’t do anything right. Iowa beat them 38-0, and Ohio State dusted the Badgers 34-0. 32.5 points are a lot to lay, but the Ducks want a statement win. So Dan Lanning is going to tell his offense to go for it and try to run up the score. Think 42-0 or 56-3 in this one.
2025 College Football Week 9 Pick: Oregon
BYU vs. Iowa State
- When: Saturday, October 25th. 3:30 p.m. ET
- strong>College Football Week 9 Odds: BYU +120 / Iowa State -143
It’s tempting to go with BYU in this spot. Iowa State has played some lousy football in a couple of games, and BYU is undefeated. However, the line has moved a whole point in a matter of minutes, not even hours, so it’s apparent that many believe the Cougs are due for a letdown.
The thinking makes sense. BYU should have lost to pesky Arizona in Tucson a couple of weeks ago. In their last, the Cougars beat rival Utah 24-21 in an emotional and physically exhausting game. Iowa State covers at home.
2025 College Football Week 9 Pick: Iowa State
UCLA vs. Indiana
- When: Saturday, October 25th. 12:00 p.m. ET
- strong>College Football Week 9 Odds: UCLA +1200 / Indiana -3333
Everybody’s going crazy for the Hoosiers. Let’s be clear, Indiana is a good team, but Indiana has a single top win this season. Sure, it happened in Autzen versus the Oregon Ducks.
Oregon may have taken the Hoosiers lightly in that game, though. Also, Oregon could be overrated in some sense. UCLA is on a roll after beating Maryland 20-17 in their last. The Bruins showed that they can win a defensive struggle. Don’t be surprised if the Bruins are down by 7 or 10 points heading into the fourth.
2025 College Football Week 9 Pick: UCLA
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*All stated odds are subject to change without prior notice.
